Apollo 13 was originally bred by Colorado-based seed bank Brothers Grimm Seeds, which pollinated a female Genius plant said to be a Jack Herer phenotype with pollen from a P75 male to conjure this coveted hybrid strain. Used by breeder Subcool from TGA genetics, Apollo 13 played a parental role in the development of several other popular strains, including The Void and Third Dimension (3D).

Carrying an aroma of pepper and earth with fruity undertones, the flavor profile of Apollo 13 has been described as herbal and skunky. One sample of Apollo 13 analyzed by the cannabis testing laboratory MCR Labs showcased impressive THC levels that exceeded 22%.